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Hormone (pineal) · Melatonin

Melatonin dosing — common supplement amounts and timing

The common melatonin dosing pattern — roughly 0.5-5mg taken at night — plus why timing relative to your circadian phase often matters more than amount, how formulations differ, and when to involve a clinician. Educational, not medical advice.

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This page is educational and not medical advice. See the medical disclaimer and editorial policy.

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The pineal hormone that regulates the sleep-wake cycle; widely used as a sleep aid and studied for circadian and antioxidant effects.
Educational — not medical advice

Melatonin is sold as a dietary supplement in much of the world. The amounts below are common over-the-counter ranges, provided for education — not a prescription. Follow product labeling and talk to a clinician about your situation.

Overview

Melatonin is a hormone whose most-studied variable is often timing relative to your circadian phase, rather than raw quantity. It is widely available as a supplement, and more is not necessarily better — low amounts at the right time are frequently emphasized in the research.

Common dosing pattern

Common over-the-counter amounts:

  • Frequently used in the range of 0.5-5 mg taken at night, before bed.
  • Lower amounts (around 0.5-1 mg) are often discussed for circadian timing; higher amounts are common in retail products but are not necessarily more effective.
  • Taken shortly before the desired sleep time, or as directed for jet lag / shift-work timing.

Starting low is a reasonable approach, since larger amounts can cause grogginess.

Why timing matters

A recurring theme in melatonin research is that its circadian phase-shifting effect depends strongly on when it is taken relative to your own night-time signal. This is conceptually different from a sedative, where the effect tracks more directly with amount — which is why timing is often discussed as the primary lever.

Formulation differences

Melatonin comes in formats that behave differently over time:

  • Immediate-release products release melatonin quickly.
  • Extended- or prolonged-release products spread exposure out across the night.
  • Sublingual and gummy formats differ in how quickly they are absorbed.

When to involve a clinician

Melatonin's effects vary by person and formulation, and it can interact with other medications. Product labeling and a qualified clinician are the appropriate sources for any real-world decision — particularly for children, during pregnancy, or alongside other medicines.

References & searches

To validate claims, prioritize primary literature and trial registrations. These links open external search pages.